A novel therapeutic giving cancer patients new hope.

We are focused on rapidly advancing our lead therapeutic candidate, misetionamide, for the treatment of multiple cancer types including ovarian and pancreatic cancers.

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Our Science

Disrupting cancer cell metabolism.

Our unique and novel mechanism of action selectively disrupts the energy metabolism of cancer cells leading to cancer cell death as well as impacting nuclear factor-κB (“NFκB”) which effects cancer cells’ ability for protein synthesis and DNA transcription thereby restricting cancer cell growth and proliferation.

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Our PIPELINE

Focused on Addressing Unmet Needs for Patients with Cancer.

Icon Ovarian Cancer

Ovarian
Cancer

Icon Pancreatic Cancer

Pancreatic
Cancer

Icon Additional Targets

Additional
Targets

Melanoma, Squamous Cell, Breast, Colorectal

Truly novel.
Truly important.

We are on a mission to improve therapeutic outcomes for cancer patients with misetionamide, a tumor-cell selective agent with a truly novel mechanism of action.

Misetionamide

Focused on what matters most.

In addition to demonstrating direct anti-cancer activity, misetionamide has shown pro-inflammatory cytokine suppression in preclinical studies.​

We have chosen to focus on the treatment of ovarian and pancreatic cancers as our initial indications, two conditions with a clear unmet medical need. Early clinical experience is promising.​

Participate in our ongoing pancreatic cancer study

Early Clinical Results Improve Quality Of Life

The Latest

publication

Publication Summary – Misetionamide (GP-2250)

A summary of all publications with links to full document

 
poster

Interim Open-Label Phase 1 Results of Misetionamide (GP-2250): A Small Molecule Antineoplastic That Inhibits Three Major Transcription Factors

 
publication

Mechanisms and rational combinations with GP-2250, novel oxathiazine derivative in ovarian cancer.

Mark Kim, Deanna Glassman, Katelyn F Handley, Adrian Lankenau ahumada, Emine Bayraktar, Nicholas B. Jennings, Robiya Joseph, Robert L. Coleman and Anil K. Sood.

 
publication

Antineoplastic activity of GP-2250 in-vitro and in mouse xenograft models

R. Duane Sofia, Kathryn M. Martin and James C. Costin